Recent work has been largely confidential, however here is a selection of published manuscripts. A full list is available on request.
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Graves R, Francis M, Smith L, Cook J, Adie EJ (2006), GPCR Internalization Measured by Image Analysis. Book chapter in Handbook
of Assay Development in Drug Discovery by Lisa K Minor (Edition: 1st ISBN10: 1574444719 ISBN13: 9781574444711) |
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Adie E J, Francis M J, Davies J, Smith L, Marenghi A, Hather C, Hadingham K, Michael N P, Milligan G, Game S (2003), CypHer 5: A Generic Approach
for
Measuring the Activation and
Trafficking of G Protein-Coupled Receptors
in Live Cells Assay and Drug Development Technology 1:251-260 |
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Murphy S, Capper S J, Hancock S M, Adie E J, Roquemore E P, Price-Jones M, Game S, Swinburne S (2003), Is z’ the best assessment of the quality of cellular assays delivering higher content? Society of Biomolecular Screening 9th conference. |
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Adie E J, Kalinka S, Smith L, Francis M J, Marenghi A, Cooper M E, Briggs M, Michael P, Milligan G, Game S (2002), A pH-sensitive fluor, CypHer 5, used to monitor agonist-induced G-protein-coupled receptor internalisation in live cells BioTechniques 33:1152-1157 |
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Roquemore E P, Adie E J, Cox H, Roche K, Davies J, Stubbs S, Francis M J, Michael N P and Thomas N (2002), High-Throughput Multi-parameter Single Cell Analysis Society of Biomolecular Screening 8th conference. |
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Turner J, Murphy S, Adie E J, Williams A and Price-Jones M (2002), High throughput multiplexed cellular toxicology Society of Biomolecular Screening 8th conference. |
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Milligan G, Kim G D, Mullaney I, Adie E J (1995), Regulation of cellular Gs alpha levels and basal adenylyl cyclase activity
by expression of the beta 2-adrenoceptor in neuroblastoma cell lines Mol Cell Biol 149-150:213-6. |
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Adie E J, Milligan G (1994), Agonist regulation of cellular Gs alpha-subunit levels in neuroblastoma x glioma hybrid NG108-15 cells transfected to express different levels of the human beta 2-adrenoceptor Biochem J 300:709-15. |
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Kim G D, Adie E J, Milligan G (1994), Quantitative stoichiomety of the proteins of the stimulatory arm of the adenylyl cyclase cascade in neuroblastoma x glioma hybrid, NG108-15 cells Eur J Biochem 219:135-43. |
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Adie E J, Mullaney I, McKenzie F R, Milligan G (1992), Concurrent
down-regulation of IP prostanoid receptors and the alpha-subunit of the stimulatory guanine-nucleotide-binding protein Gs during prolonged
exposure of neuroblastoma
x glioma cells to prostanoid agonists.
Quantification and functional implications Biochem J 285:529-36. |
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